fungal cell wall — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9000	Pyrimorph		Antifungal
	Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici. Pyrimorph inhibited different stages in the life cycle of P. capsici including mycelial growth, sporangium production, zoospore...		Antifungal
PDK0101	4-Methylcinnamic acid		Antifungal
	4-Methylcinnamic acid is a cinnamic acid analog that can be used as an intervention catalyst to overcome antifungal tolerance. 4-Methylcinnamic acid can improve the potency of cell wall-disrupting agents.		Antifungal
T1799	Caspofungin Acetate	L 743873,Cancidas,MK 0991,L 743872	Antibiotic , Antifungal
	Caspofungin Acetate (MK 0991) is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. This agent is active against Aspergillu...		Antibiotic , Antifungal
T6686	Sulconazole mononitrate	Exelderm,Sulconazole Nitrate,RS 44872	Antibacterial , Antibiotic , Antifungal
	Sulconazole mononitrate (Exelderm) is the nitrate salt form of sulconazole, a synthetic imidazole derivative with the antifungal property. Sulconazole mononitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demeth...		Antibacterial , Antibiotic , Antifungal
T61355	APX2039	APX-2039,APX 2039	Antifungal
	APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity against C. neoformans and C. gattii.APX2039 exhibits potent an...		Antifungal
T0146	Tioconazole	UK-20349,Vagistat	Antibiotic , Antifection , Antifungal
	Tioconazole (Vagistat) is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and pr...		Antibiotic , Antifection , Antifungal
T19721	Epoxiconazole	BAS-480F,BAS 480F,EC 406 850 2,BAS480F,EC-406-850-2	Antifungal
	Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation.		Antifungal
T2213	Terconazole	Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,R42470	Antifection , Antifungal
	Terconazole (Terazol 7) is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damag...		Antifection , Antifungal
T61194	D75-4590		Others
	D75-4590 is a β-1,6-Glucan inhibitor. As glucan is a major component of the cell wall, specifically β-1,6-Glucan, D75-4590 can fight fungal infections by inhibiting its synthetase.		Others
TN1569	Deoxylapachol		Antifection , Antifungal
	Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevi...		Antifection , Antifungal
T71341	Myclobutanil hydroxide
	Myclobutanil hydroxide is a 14-α demethylase inhibitor that inhibits ergosterol synthesis and fungal cell wall formation. It also weakly inhibits testosterone production.
T68780	Puupehenone
	Puupehenone is a natural heat shock protein 90 (Hsp90) inhibitor, potentiating the echinocandin drug caspofungin in caspofungin-resistant fungal pathogens, blocking the induction of caspofungin-responding genes required ...
T63392	Chitin synthase inhibitor 5
	Chitin synthase inhibitor 5 effectively blocks chitin synthase, a key enzyme in fungal cell wall formation, with a low IC50 value of 0.14 mM. Chitin synthase inhibitor 5 demonstrates broad-spectrum antifungal activity ag...
T79413	Antifungal agent 73
	Antifungal agent 73 (compound A32) effectively combats azole-resistant candidiasis by disrupting the fungal cell wall and membrane. It demonstrates potent in vivo activity against pathogenic fungi, including fluconazole-...
T75686	Enfumafungin
	Enfumafungin, a triterpene glycoside extracted from Hormonema carpetanum fungus, acts as an antifungal by inhibiting (1,3)-beta-D-glucan synthase, crucial for fungal cell wall synthesis. It selectively targets yeasts and...
T41322	Dimethomorph
	Dimethomorph is a morpholine fungicide belonging to the fungicide group of sterol biosynthesis inhibitors that inhibits fungal cell wall formation. Dimethomorph inhibits mycelial growth of the oomycete fungi, P. citropht...